Dental Amalgam, FDA Docket 03N-0169

Volume 1

ADA submission -bibliography c1-vol1.pdf (A+/P)

(see www.flcv.com/adaabsr.html

scientific articles & URLs c2 (A)

letter from Maine Dental Assoc. c3 (NS)

letter from ADEA c4 (NS)

Hal Huggins letter sumarizing experience with 2500 patients, including 1000 with MS and documentation c6 (A+)

Stuart Schekner(DDS) personal case history and study c7 01-03 (A)

Debbie Bevel- personal case history c8 (A)

Paul Moller letter and study supp 1-01 to 03 (A)

Robert Siblerud letter with 14 studies he authored supp 2 01 to 016 (A+)

H Huggins, letter regarding mercury test, test experience, and British Gulf War Disease cases

Supp 3- 01 vol 1 (A)

Sweden The Dental Material Commission - Care and Consideration -M Berlin

supp3- 01 vol4 (A+)

H Huggins, T Levy, paper- CF Protein Changes in MS after amalgam removal, 1998

Supp 3-02 (A)

newspaper article on over 100,000 veterans with Gulf War Disease Supp 3-03 (NS)

H Huggins, paper- Recovery from Gulf War Disease Supp 3-04 (A-)

S Langworth, Huddinger Hospital paper Supp 4-01 (P-)

C.K. Bleslus et al, Dental Amalgam and Mercury, Biological Therapy, Vol XIII, 1995

Supp 5 (A)

Pam Factor-Litvak et al Mercury derived from dental amalgam and neuropsychologic function 2003 Supp 6-01 (P)

articles with URLs c2-01 (A)

rest are duplicates of the above submissions

Volume 2

runagain@juno.com Case history and documentation, emc 01 (A)

Dr. Vera Stejskal- MELISA study- effects of mercury immune reactivity(1998) emc1-01 (A)

Michael Davis, DDS, articles on amalgam, emc2 (A)

Steve Markus, DDS letter with information c3 (A)

Pat King, letter, personal case history c4 (A)

Nancy Richards, bibliography of articles c5 (A)

L.Campbell, bibliography of articles c6 (A)

David Kennedy, DDS summary and bibliog & IAOMT summary c7 & c7-01 (A+)

B. Windham(DAMS) FS1(amalgam is largest source of exposure in most)

over 100 peer-reviewed studies including large NIDR military population study

www.flcv.com/damspr1.html c8 (A+)

B. Windham(DAMS) FS2f (amalgam is largest source of mercury in sewers and sewer sludge and thus major source in water bodies, fish, wildlife, crops, rain-since outgased from soil- 30% of U.S. lakes and similar for rivers and most bays have warnings for mercury in fish) www.flcv.com/damspr2f.html c9 (A+)

B. Windham(DAMS) FS3 Common adverse health effects caused by mercury from amalgam, www.flcv.com/damspr3.html c10 (A+)

B Windham(DAMS) FS4 common developmental neurological conditions caused by mercury and toxic metal exposure including ADHD, learning disabilities, etc. and the connection to juvenile delinquency, criminality, violence. c11 (A) www.flcv.com/damspr4.html

B Windham(DAMS) FS6 Health effects to dentists and dental staff caused by occupational exposure to mercury. www.flcv.com/damspr6.html c12 (A+)

B Windham(DAMS) FS7 Common oral conditions caused by dental amalgam, www.flcv.com/damspr7.html c13 (A+)

B Windham(DAMS) FS8 Endocrine, developmental, and reproductive effects of mercury from amalgam. www.flcv.com/damspr8.html c14 (A+)

B Windham(DAMS) FS9 The mercury connection to common neurological and immune related chronic degenerative health conditions (MS,CFS,FM,ALS,PD,Lupus,AlzD,RA, Depression,ADD,etc.) www.flcv.com/damspr9.html c15 (A+)

B Windham(DAMS) FS12 Documentation that amalgam is the largest source of mercury in most and of methyl mercury in many. c16 (A+) www.flcv.com/damspr12.html

B Windham(DAMS) FS13 Mercury Vapor Causes Neurological Developmental and Behavioral Effects at Lower Levels than Other Forms of Mercury. emc17 (A+)

www.flcv.com/damspr13.html

B Windham(DAMS) FS14 The mercury connection to allergies and immune reactive conditions. www.flcv.com/damspr14.html c18 (A+)

B Windham(DAMS) FS16 Studies document high mercury exposures from dental amalgam fillings and fish and common adverse neurological and cardiovascular effects.

www.flcv.com/damspr16.html c19 (A+)

B Windham(DAMS) FS20 Amalgam is the largest source of mercury in most and of methyl mercury in many-methylation. www.flcv.com/damspr20.html c20 (A+)

B Windham(DAMS) FS17 Blood tests not reliable indicator of mercury body burden or mercury toxicity. Better options are available. High mercury body burden and mercury toxicity and effects are even more common than acknowledged due to failure of the blood test to identify most of those affected. Doctors with experience at treating mercury toxicity mostly use other tests. c21 (A+)

www.flcv.com/damspr17.html

Engel P, "Health Observations Before and After Amalgam Removal", Schweiz Monatsschr Zahnmed 1998;108(8):811‑3 www.amalgam‑info.ch/engel.htm c22 (A+)

Dr. M Hanson research suggested; c23

The Dental Material Commission ‑‑ Care and Consideration' assigned Maths Berlin, in autumn 2002, to report on the past five years' research literature on amalgam and the health hazards, if any, of mercury. Professor Berlin compiled the environmental medicine risk analysis of mercury and amalgam issued by the Swedish Council for Planning and Coordination of Research (FRN) in 1998 (FRN, Report 1998:22). This risk analysis was based on literature published between 1993 and November 1997. The present risk analysis builds further on this material, and analyses literature published between November 1997 and November 2002. c24 (A+)

Mercury in brain tissue of infants

Eggleston D W, Malmström C, Nylander M , Necropsy studies clearly showed higher mercury (Hg) concentrations in bulk tissue of brain stem tissue from 26 infants compared with brain tissue of the occipital lobes from 21 adults of the same population in California, USA (Table 1). c25

Amalgam derived mercury in feces, Christer Malmström DDS, Mats Hansson PhD

och Magnus Nylander MD, DDS, ISTERH Third International Conference

and NTES Fourth Nordic Conference on Disease. Stockholm (Huddinge), may 25 ‑ 29, 1992. http://home.swipnet.se/misac/forskning7.html c26 (A)

Gopal KV. Neurotoxic effects of mercury on auditory cortex networks growing on microelectrode arrays: a prelimary analysis. Neurotoxicol Teratol 2003 Jan‑Feb;25 (1):

Pages 69‑76 c27 (A)

Bartova J, Prochazkova J, Kratka Z, Benetkova K, Venclikova Z, Sterzl I. Dental Amalgam as one of the risk factors in autoimmune diseases. Neuroendocrinol Lett 2003 Feb‑Apr;24(1‑2): pages 65‑7 c28 (A+)

Titovets E, Nechipurenko N, Griboedova T, Vlasyuk P. Acta Neurochir Suppl 2000;76:

Pages 279‑81 c30 (A)

Lymberi P, Hirsch F, Kuhn J, Ternynck T, Druet P, Avrameas S. Autoimmunity induced by HGC12 in Brown‑Norway rats. II. Monoclonal antibodies sharing specificities and idiotypes with mouse natural monoclonal antibodies. J Immunol 1986 May 1;136(9):Pages 3277‑81 c31 (A)

Hirsch F, Kuhn J, Ventura M, Vial MC, Fournie G, Druet P. J Immunol 1986 May 1;136(9):

Pages 3272‑6 C32 (A)

Shenker BJ, Pankoski L, Zekavat A, Shapiro IM. Mercury‑induced apoptosis in human lymphocytes: caspase activation is linked to redox status. Antioxid Redox Signal 2002

Jun;4(3):Pages 379‑89 c33 (A)

Wiatr Halny personal case history, with bibliography of articles c34 (A)

G.H. Smith, DDS Bibliography of science articles showing harm c35 (A+)

Studies demonstrating a correlation between amalgam dental fillings and brain mercury levels:

Lakartidningen 1986 Feb 12;83(7):519‑522; Swedish Dental Journal 1987;11(5):179‑187

Sci Total Environ 1987 Oct;66:263‑268; J Prosthet Dent 1987 Dec:58(6):704‑707

FASEB J 1989 Dec;3(14):2651‑2646; Sci Total Environ 1990 Dec 1;99(1‑2):1‑22

Sci Total Environ 1993 Sep 30;138(1‑3):101‑115; J Trace Elem Med Biol 1995 Jul;9(2):82‑87

Zentralbl Hyg U:mweltmed 1996 Feb;198(3):275‑291; FASEB J 1998 Aug;12(11):971‑980

Biometals 1999 Sep;12(3):227‑231

Title: "Retrograde Degeneration of Neurite Membrane Structural Integrity of Nerve Growth Cones Following In Vitro Exposure To mercury."

Authors: Leong, CW; Syed, NI; Lorscheider, FL.

Journal: NeuroReport, 12(4):733‑737, 2001. c36 (A+)

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NeuroendicrinologyLetters Vol.23 No.5/6, Oct‑Dec 2002; Dental amalgam removal improves

health 2002; 23:459‑482 pii: NEL235602A12 PMID: 12500173 (796 patients) c37 (A+)

Large bibliography documenting amalgam is the main cause of oral lichen planus and replacing amaglam usually cures the condition c38 (A+)

MERCURY, THE ROOT OF DEPRESSION, ANGER, ANXIETY AND VIOLENCE SOURCE

Psychological Reports, 1994, 74,67‑80, Psychometric Evidence That Mercury From Silver Dental Fillings May Be An FBI Factor In Depression, Excessive Anger, Anxiety,

by Robert L. Siblerud, John Motl, Eldon Kienholz and Chicago Tribune, Probing the Violent Mind, c39 (A)

Dent Res 1998 Apr;77(4):615 24 Mercury in biological fluids after amalgam removal Sandborgh Englund G, Elinder CG, Langworth S, Schutz A, Ekstrand J

Department of Basic Oral Sciences, Karolinska Institutet, Huddinge, Sweden. c40 (A)

Oskarsson A, Palminger Hallen I & Sundberg J. Exposure to toxic elements via breast milk

Analyst 120(3):765‑770 (1995) c41 (A)

J Dent Res 1998 Jun;77(6):1415‑25 Activation of the immune system and systemic immune‑complex deposits in Brown Norway rats with dental amalgam restorations.

Hultman P, Lindh U, Horsted‑Bindslev P. Department of Health and Environment, Linkoping University, Sweden. c42 (A)

Skare I & Engqvist A Human Exposure to Mercury and Silver Released from Dental Amalgam Restorations. Archives of Environmental Health 49:384‑394 (1994) c43 (A)

Rowland AS, Baird DD, Weinberg CR, Shore DL, Shy CM, Wilcox AJ The Effect of Occupational Exposure to Mercury Vapour on the Fertility of Female Dental Assistants

Occupational & Environmental Medicine. 51(1):28‑34, 1994 Jan c44 (A)

B Windham(DAMS) "Dental Amalgam Fillings" is the Number One Source of Mercury in People and Exposure Exceeds Government Health Standards for Inorganic mercury(vapor) (annotated bibliography: references at end of summary) c45 (A+)

www.flcv.com/amalno1.html

Amalgam is the largest source of inorganic and organic mercury in most people

9. Kingman A, Albertini T, Brown LJ, Mercury concentrations in urine and whole blood associated with amalgam exposure in a US military population., J Dent Res 1998 Mar;77(3):461‑71 (population of over 1000 Air Force personnel; found each 10 amalgam surfaces increased mercury in urine by approx. 1 microgram per liter)

11. Leistevuo J et al, Dental amalgam fillings and the amount of organic mercury in human saliva. Caries Res 2001 May‑Jun;35(3):163‑6; &

12. Sellars WA, Sellars R. Univ. Of Texas Southwestern Medical School "Methyl mercury in dental amalgams in the human mouth", Journal of Nutritional & Environmental Medicine 1996; 6(1): 33‑37 c46 (A+)

B Windham(DAMS) Mercury Vapor Causes Neurological Developmental and Behavioral Effects at Lower Levels than Other Forms of Mercury; & Amalgam is largest source of exposure. review and references

www.flcv.com/damspr13.html c47 (A+)

B Windham(DAMS) Documentation of Common Cardiovascular Health Effects from Mercury Amalgam, review and references, c48 (A+)

B Windham(DAMS) Mercury‑Caused Endocrine Conditions Causing Widespread Adverse Health Effects, Cognitive Effects, and Fertility Effects , review and references,

www.flcv.com/endohg.html c50 (A+)

Claire Wachter, personal case: Hashimoto's disease c51

Marilynn Carter Bibliography of science articles c52 (A)

Karen Snyder Personal case: recovery from disability after amalgam replacement c53 (A)

Marie Flowers Bibliography of science articles c55 to c88 (A+)

Kazantzis G. Mercury exposure and early affects: an overview Med Lav 2002 May‑Jun: 93(3)

pages: 139‑147 c89 (A)

B Windham(DAMS) Depression and other Neurotransmitter Related Conditions‑ the mercury connection; review and references, www.flcv.com/depress.html c91 (A+)

B Windham(DAMS) Infertility, Birth Defects, and Fetal Developmental Effects Related To Mercury From Amalgam Dental Fillings, review and over 150 references,

www.flcv.com/fetaln.html c92 (A+)

B Windham(DAMS) Oral galvanism and Electromagnetic Fields(EMF): factors along with mercury's high volatility and extreme toxicity in significant exposure levels and oral effects from amalgam fillings. review and references c93 (A+)

www.flcv.com/galv.html

B Windham(DAMS) Documentation of high exposure levels to mercury from dental amalgam and the mechanisms by which mercury from amalgam causes over 30 chronic health conditions; with documentation of over 50,000 clinical cases of recovery or significant improvement from all of those conditions after amalgam replacement; review and over 3,000 peer-reviewed references. www.flcv.com/amalg6.html

c94 c94-01 c95 (A++)

B Windham(DAMS) Blood tests not reliable indicator of mercury body burden or mercury toxicity. Better options are available. High mercury body burden and mercury toxicity and effects are even more common than acknowledged due to failure of the blood test to identify most of those affected. Doctors with experience at treating mercury toxicity mostly use other tests. www.flcv.com/damspr17.html c96 (A)

B Windham(DAMS) Below is the URL of a review of over 100 peer‑reviewed studies that documents the endocrine system effects of mercury from amalgam, which affects millions of people. www.flcv.com/endohg.html c97 , c97-01 (A+)

B Windham(DAMS) Below are URLs (with attached files‑take your choice) of papers with peer‑reviewed studies that document the mechanisms by which mercury from amalgam causes CFS, Fibromyalgia, Lupus, ALS, Alzheimer's, Parkinson's Disease, MS, etc. c98

www.flcv.com/cfsfm.html c99-01 (A+)

www.flcv.com/als.html c100-01 (A+)

www.flcv.com/parkins.html c100-02 (A+)

www.flcv.com/ms.html c100-03 (A+)

www.flcv.com/alzhg.html c100-04 (A+)

Mary Ann Newall Bibliography of Science articles showing amalgam harm c101 (A+)

Mary Ann Newall Bibliography of Science pre-1996 science articles c102 (A)

Mary Ann Newall Bibliography of Science articles showing amalgam harm c103 (A+)

Mary Ann Newall Bibliography of Science articles showing amalgam harm c104 (A+)

Paul Rubin, DDS, Bibliography of Science articles showing amalgam harm c105 (A+)

CSDA letter C106 NS

1:) 150 Years of Dental Amalgam by F. Berglund (with permission of the author) on published case report of amalgam poisoning and amalgam allergy (122 studies & 123 studies resp).

It seems more than a coincidence that dentistry readily acknowledges that there are published report of amalgam allegy but somehow seems to have missed just as many reports of poisoning. c107-01

2:) Health effects of amalgam removal. 22 studies involving 4611 patients by Mats Hanson. This meta analysis will be included in the current Dental Materials Evaluation by the Dept. of Health, Sweden. c107-02

Mats Hanson, PhD, Fellow of the IAOMT (US/Can), Scientific committee of the Swedish IAOMT, Scientific advisor to the Assoc. Sw. Dental Mercury Patients (sister organisation to DAMS, USA), member of the Internat. Reference Group of the Metal Biology Ctr, Uppsala Univ, Sweden c107 01 & 02 (A+)

***********

Stuart Schecter, DDS Article c108-01

Marie Flowers Science Articles c109 to c115 (A+)

Paul Moller Article c116 (A)

Marie Flowers Science article c117 to c121

Maryanne Rygg Bibliography of science articles c122 (A+)

Dr. J.M. Hardy, DMD, Bibliography from his book: Mercury-Free : The Wisdom behind the global consumer movement to ban silver dental fillings" c123 -01 (A+)

Dwight Florence Bibliography of science articles showing amalgam harm c124 (A)

Leslie Joy Smith Bibliography of science articles showing amalgam harm c125 (A)

Ann Meyer Bibliography of science articles showing amalgam harm c126 (A)

Letter from Lousiana Dental Association, c127 NS

Lyle & Trish Brown URLs of web sites documenting harm from amalgam c128 (A)

duplicates again:

runagain@juno.com Personal case and documentation c1 (A)

Michael Davis, DDS Letter and documentation c2 (A)

Steve Markus, DDS Letter and information c3 (A)

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