Causes
& Natural Measures to Prevent and Treat Autoimmune Conditions
B Windham
(Ed) DAMS Intl
A
utoimmune diseases
occur when the body’s immune system is attacked by its own tissues instead of
foreign agents like bacteria. it is our immune system’s job to fight off
pathogens, like viruses, bacteria, and parasites, and to notice the difference
between these pathogens and our own healthy tissue. Statistics show that over
24 million Americans are currently living with an autoimmune disease and these
numbers are predicted to rise. Many more suffer from chronic health problems.
There are more than 80 different autoimmune diseases and at least 15 of these
are considered common. (5b,24,40,52,87) In
the majority of
cases of chronic health problems, undiagnosed parasitic, dental jawbone, or
other infections along with acute or cumulative toxic metal or other toxin exposures
are the main cause or a significant factor (2,3,5b,24,40,52,
87
, etc.).
There are three main
ways through which toxins get into the body—ingestion (mainly through food and
water), inhalation, and absorption by the skin (through direct contact via
clothing, applied substances, air, or water). Some toxins end up being stored
in the muscle, fat, bones, or other soft tissues for long periods.
Dr. Yu and many of
the other doctors and dentists referenced here point out that millions of
patients have medically unexplained symptoms and suffer and die from conditions
like ALS, MS, ALZ, Parkinson’s, CFS, Mood Disorders, Cancer, etc. -that could
be cured or significantly improved, but have underlying immune system disabling
factors that usually include parasitic infections, dental infections
(root-canaled teeth, jaw- bone cavitation infections, gum disease), toxic metal
toxicity or other toxins, nutritional factors, etc. These conditions can be
tested for and treated by knowledgeable doctors or dentists and usually improve
(87,2,3,4,5,52), but most doctors and dentists in the U.S. do not have proper
training to know what to test for or how to test for chronic conditions
underlying immune disabling problems (87, etc.).
15 of the
most common chronic autoimmune conditions include:
Multiple sclerosis (
characterized
by damage to the myelin sheath of the brain and spinal cord)
Lupus: (
immune system attacks healthy tissue and organs due to the
Inflammation caused by lupus
)
;
Diabetes:
(pancreas cannot produce enough insulin to lower the sugar
levels in the blood);
Rheumatoid arthritis (RA):
(the immune system attacks the joints);
Psoriasis/psoriatic arthritis:
(the skin cells
build up instead of shedding when they need to- forming red, inflamed patches
);
;
Inflammatory bowel disease (IBS):
(includes Crohn’s
disease and ulcerative colitis which affects the gastrointestinal system and
causes inflammation
)
;
Addison’s disease:
(the adrenal cortex is damaged and does not
make enough of the hormones cortisol and aldosterone);
Graves’ disease:
(the thyroid produces too much of the hormones
that control the body’s energy levels);
Sjögren’s
syndrome:
(leads to dry eyes and
mouth because the glands that provide lubrication are attacked
)
;
Hashimoto’s thyroiditis:
(immune system attacks the thyroid gland
causing it to become underactive (hypothyroidism);
Hypothyroidism:
(not
enough hormone produced to fully activate production of thyroid gland or
enzymes not converting to active thyroid hormone)
Myastheniagravis
: (
affects nerve impulses
that control the contracting and relaxing of muscles ,leading to muscle
weakness
)
;
Autoimmune vasculitis: (
The blood vessels are attacked which narrows
the arteries and veins
)
;
Pernicious anemia:
(leads to vitaminB12 deficiency and the blood
being low in normal red blood cells
)
;
Celiac disease:
(The immune system attacks the small intestine
when it contains gluten
)
.
Methods and
foods to prevent and control these are found in (5,21,26,33,40,52) - more
details for toxic metals
here.
High dose vitamin C
is usually
beneficial in reversing chronic health conditions, including
viral conditions
like Coronavirus.
The two
factors that contribute to autoimmune diseases are environmental and genetic
(involve gene mutations). Environmental causes of autoimmune disease are one of
three things- dietary factors, infections, or toxins. Everyone has toxic
exposures and they are additive or
synergistic
,
causing oxidative damage, neurological excitotoxicity, chronic inflammation,
and
endocrine system disruption
(31)- factors in autoimmune disease.
The liver, kidneys, skin, digestive system,
and lungs all work together to rid our bodies of toxic substances, but
sometimes they are overwhelmed by acute or cumulative exposures.
4 of the common factors causing autoimmune
conditions that are commonly caused by toxic exposures are oxidative stress,
endocrine disruption(31), dysbiosis, and genotoxicity. Some are more
susceptible
to chronic conditions
due to genetic factors or past exposures or immune system status.
Studies have shown that
heavy metal poisoning
due to the metals
mercury
and cadmium
has been linked to the autoimmune diseases-
lupus, multiple
sclerosis, Parkinson’s disease, Amyotrophic Lateral
Schlerosis
,
Hashimoto’s thyroiditis, Graves’ disease, rheumatoid arthritis, pernicious
anemia, Diabetes, Autism, ADHD, Alzheimer’s, Myasthenia Gravis, and more.
(2,3,4,5b,24,27,35,52,85a&86)
Exposure to high levels of cadmium can also affect the kidneys and can cause
renal failure and bone demineralization, which means that the bones lose their
calcium (3,4,5b). It has also been suggested that having a nutritional
deficiency in calcium, iron, protein, and/or zinc is a risk factor. Cadmium
poisoning can occur from food or water that came from a contaminated source.
Apart from cigarettes or industrial exposure, foodstuffs are the main source of
cadmium exposure for non-smokers. The foods most likely to lead to cadmium
exposure are cereals, vegetables, nuts and pulses, chocolate and cocoa, starchy
roots or potatoes, and meat products. Much more on mercury toxicity effects
here
. A large review study
found mercury had a strong risk factor for ALS (28) and other toxic metals and
welding work also had positive risk factors. Another study found a positive
association of lead exposure with ALS (28).
Due
to the widespread significant levels of toxic metals in food, fluoridated
water, and medicine, most people have levels of toxic metals that are adversely
affecting their health and should get tested and consider detox (36,32).
Cardiovascular
disease is an increasing problem worldwide and Toxic exposure is a significant
factor in the incidence of
cardiovascular
disease
by interfering with thrombosis, thermogenesis, blood pressure
regulation, atherogenesis. Drug and
toxin
exposure
in expectant mothers has been associated with cardiac birth
defects and the premature onset of cardiovascular disease in the child.
Exposure to
heavy metals
(like
lead, arsenic, aluminum, mercury, nickel, and cadmium), solvents, pollutant
gases,
pesticides
, and
herbicides has been linked to the
onset of cardiovascular disease
.
Lead poisoning can
cause problems relating to high blood pressure and can damage the nervous
system, reproductive system, kidneys, liver, and brain (3,4,5b,27d,35). A large
EDF (Environmental Defense Fund) showed that 20% of baby food samples they
tested contained lead (39). Their study concluded that more than a million
children consume more than the lead limit set by the FDA which means that
children are being predisposed to autoimmune diseases and neurological problems
from a young age. Studies have also found significant levels of lead in fruit
juices, root vegetables, leafy green vegetables, chocolate and cocoa powder,
organic food, spices, and candy.
B
etween January 1, 2015 and March 31, 2018. In 2018, nearly 2
million people were served by drinking water systems that had health-based
violations of the lead drinking water rule (37). Additionally, 5.5 million
people were served by drinking water systems that exceeded EPA’s Action Level
for lead between January 1, 2015 and March 31, 2018.
Many studies have shown lead exposure has
significant effects on children’s neurodevelopment, attention, and IQ. (2,3,35)
A large review study showed lead with a significant risk factor for ALS,
Alz
., Parkinson’s (27d,28) & also is associated with
several kinds of cancer (41).
Arsenic
is extremely poisonous
to people
and
most commonly found in water or rice bran. There are two types of arsenic:
organic and inorganic -the more dangerous type. Arsenic can also be found in
foods like fruit and vegetables, and seafood in small traces. Just as in the
case of lead poisoning, children seem to be more susceptible to arsenic
poisoning and are often exposed through pressure treated lumber. Arsenic is
endocrine disrupting (31) and documented to cause several types of cancer (41).
Heavy metal
poisoning is extremely common causing oxidative stress, chronic inflammation,
and reactive oxidative species which commonly leads to a variety of
autoimmune diseases
and
neurological conditions
including
atherosclerosis,
diabetes, Parkinson’s, MS, ALS, Lupus, cancer, etc. (3).
Heavy metals including cadmium, arsenic, mercury, lead,
nickel, are documented to cause or be a factor in several types of cancer (41).
Most people accumulate significant levels of toxic metals over time. Anyone
with chronic health issues should get periodically tested for toxic metals
(32,33) and detoxify if needed. Since the food system is highly contaminated
with toxic metals and pesticides, avoid the most highly contaminated types as
discussed in the references to this paper (large fish usually have the highest
mercury level and avoid
GMO foods
).
In addition to IV detox methods there are
supplements such as modified citrus pectin or cilantro & chlorella
supplementation can be used (5,21). Foods useful in detox include
Garlic, Wild
blueberries, Barley grass juice powder, Wheatgrass powder, Spirulina, Curry,
Green Tea, Tomatoes, Atlantic dulse, and lemon juice in water (5). If doing IV
detox, a mineral supplement to replace essential minerals, plus probiotics, may
be needed.
EDCs are
substances in the environment, our food, and common household products that
interfere with hormone production, metabolism, and function in the body.
Because they disrupt hormones — and hormones control almost every bodily
function — they have been
linked
to reproductive disorders,
breast development and cancer, prostate cancer, and thyroid function, which
affects obesity and overall metabolism. (75)
EDCs are known to mimic the action of
steroid hormones. Accumulating evidence points to EDCs as being a significant
concern for public health.
In the
past 3 or 4 decades, thousands of new chemicals have been introduced into the
environment as common agricultural and consumer products. These chemicals are
ingredients commonly found in agricultural and household insecticides,
fungicides, and herbicides. A large range of compounds is thought to cause
endocrine disruption- toxic metals, dioxin, DDT, BPA, phthalates, perchlorate,
parabens, many pesticides and herbicides, and certain pharmaceuticals. EDCs can
be found in many items we use on a daily basis such as plastic water
containers, food tins, food additives, and detergents, and processed food.
They have
been linked to several autoimmune conditions such as rheumatoid arthritis, type
1 diabetes, thyroiditis, and systemic lupus erythematosus (SLE). The existing
literature
proves that EDCs have a role in the
cause of obesity, diabetes, and cardiovascular problems. (76)
In terms of our food supply, PCBs and dioxins have been
banned since the 1980s, yet still linger in the environment and the food chain.
Dioxins, another EDC, are found mainly in meat and dairy —so eating a
plant-based diet offers protection from these.
While it
is difficult to completely avoid EDCs, it is possible to reduce your exposure.
Avoid as many harmful household chemicals as possible, and look for
eco-friendly, “green” alternatives. Eat the highest quality, freshest organic
food you can find. Help your body to detox itself by hydrating with filtered
water, exercising, and eating a high-fiber diet. Use glass, steel, bamboo, and
ceramic food containers.
There is a strong
link between
Pesticides
and autoimmune
diseases. Millions of people are poisoned by pesticides each year (20), and millions
of people are drinking water containing pesticides or pesticide
degradates
(20b).
2-4-D is one of the most used
herbicides and per its fact sheet is :
Long
lived; Acutely toxic with damage to blood, liver, and kidney;
Endocrine
disrupting
:
adversely affects thyroid and gonad function; exposure
results in 3-fold increase in Parkinson’s disease risk(27); Neurotoxic: affects
brain and brain functions; mounting body
of evidence supports association with
NHLymphoma
(30).
In
addition to the wide range of health problems
caused by pesticide exposures, pesticides are also causing large reductions in
bird and pollinator species and insects in general, and a significant factor in
the anti-biotic resistance crisis.
Studies have shown that farming with
agricultural pesticides
or herbicides or other
chronic exposure to pesticides has been known to cause
Asthma
,
Arthritis/Osteoporosis
,
Celiac Disease
,
Diabetes
,
,
Hepatitis
,
Hypersensitivity
,
Lupus
,
Multiple Sclerosis
(27c)
,
Parkinson's Disease
(27),
Alzheimer’s Disease
(27),
Amyotrophic Lateral
Sclerosis (ALS)
,
Dementia
(27,30b,
etc.);
Myasthenia Gravis(85).
Pesticides, chemical and industrial exposures have been found to be associated with systemic lupus erythematosus (34a). These include pesticides and solvents, and experimental findings also support investigation of specific agents including organochlorines and trichloroethylene . Experimental findings and biologic plausibility suggest research on SLE and occupational exposure to hydrocarbons (i.e., mineral oils) is warranted, especially given the widespread exposures in the population. Experimental and limited human findings support further investigation of SLE related to mercury exposure, especially in dental occupations.
Pesticide
poisoning has been found to cause birth defects, infertility and other
reproductive problems, damage to the brain and nervous system, ADHD,
developmental and motor problems, damage to the liver, kidneys, lungs,
rheumatoid arthritis, lupus, and other body organs, many types of
cancer
(13,20,30b);
& to be a significant risk factor for ALS
(28,30b). Many studies have found chronic exposures to pesticides or herbicides
(by farming or occupational exposure or use for private gardens or lawns) to be
a risk factor for ALS (28). Some studies found a positive association of ALS
with exposure to paint thinners or removers, formaldehyde, exposure to
organophosphate or pyrethrin pesticides or herbicides or fumigants (28). Three
studies found epigenetic allele form to be a factor in disease susceptibility
for ALS (& other conditions). Mutated allele forms of genes that detoxify
pesticides and reduce detoxification capacity were strongly associated with ALS
susceptibility. (28pqr) Note that toxic exposure can cause such mutations that
increase susceptibility.
Most of the
common pesticides including organophosphates and carbamates, fumigants,
organochlorines, pyrethroids and Chlorpyrifos have been shown to have a toxic
effect on humans causing ADHD, developmental and psychomotor effects,
respiratory effects, and are factors in autoimmune conditions. (5b,7-11,35,60)
Pesticides,
Herbicides, Pyrethroids, POPs (DDT& beta-HCH) and Occupational exposure to
pesticides have been found to be associated with diabetes-T1D & T2D. (59)
Exposure to pyrethroids was associated with a three-fold increase
in the risk of cardiovascular disease mortality and diabetes (29) and the most
highly exposed occupational quartile had more immune system and genotoxic
effects (29b). Endocrine disrupting chemicals have been found to have effects
on psychomotor function and attention and to be a factor in obesity
(31,34,35a,38).
Many
pyrethroids, that are commonly used to control insects in household
insecticides, pet sprays and shampoos, are known to have estrogenic activity
(31) and may provoke an autoimmune response due to their ability to create
oxidative stress.
Organophosphates and carbamates
are toxic to the
nervous systems of animals and humans. Both are common causes of poisoning and
poison-related deaths worldwide
.
Aldicarb
and methomyl are the most common causes of human poisoning from carbamates. The
most common organophosphates are chlorpyrifos, diazinon,
dursban
,
fenthion, malathion, and parathion.
Organochlorines
have been used in the past to control malaria
and typhus, etc.
Most commonly used in
developing countries, particularly in Asia, they have had detrimental effects
on the environment because it is highly toxic to bees, fish, animals, and other
living organisms. Human exposure is also considered dangerous as it has been
known to cause symptoms of neurological damage and endocrine (hormonal)
disorders.
Pyrethroids
come from the flowers of
pyrethrins
.
It works by targeting the sodium channels in the organisms it aims to remove-.
causing giddiness, headache, vomiting, muscle twitching, low energy,
convulsions and sometimes loss of consciousness in those who have been exposed.
Chlorpyrifos
is one of the most commonly used for
agricultural purposes- used on crops like corn, soybeans, broccoli, and apples.
Other foods that often test positive for pesticide residue are peaches,
peppers, nectarines, and cilantro. This pesticide has been shown to impair children’s
brain development.
Fumigants
are often used to kill insects that infest
stored food. Fumigation should only be done by a licensed professional because
of its toxicity to animals and humans. The most commonly used fumigants are
hydrogen cyanide, naphthalene, nicotine, and methyl bromide.
To limit
your pesticide exposure, buy organically grown fruit and vegetables or locally
grown no-spray produce whenever possible and wash all fresh produce before
consumption.
To
detox pesticide poisoning consider using NAC and selenium to boost your body’s
glutathione, citrus pectin, milk thistle,
Essiac
tea,
High
dose Vitamin C
,
Saunas and detox baths, Clay baths using calcium montmorillonite,
pantethine
, activated charcoal, alkaline foods, grapefruit
to burn the fat stored in your liver (5,21,33,40,52).
Volatile
Organic Chemicals
are
compounds that have a high vapor pressure and low water solubility. Many of
them are man-made chemicals that are commonly found in processed food and its
packaging — and many VOCs such as the Polyaromatic Hydrocarbons (PAHs) pose a
serious health risk (77).
Volatile
organic compounds include various types of chemicals found in gasoline,
solvents, benzene, formaldehyde, synthetic musk scents, and fragrance
ingredients. They are
widespread
in
the environment because of evaporation and the incomplete combustion of fuels.
(78)
They
can accumulate in various foodstuffs and may also form during the processing
and preparation of food. They can seep into food from its packaging materials.
VOCs have been
found
in microwaved popcorn and this has
been raised as a health concern for consumers and production workers alike.
(78c)
Bronchiolitis
obliterans is an inflammatory condition affecting the lungs’ smallest airways.
One of the
causes
is
the inhalation of chemical fumes such as volatile organic compounds. (77,78)
Many have
raised concerns about petroleum and chemical contamination of seafood after oil
spills are cleaned up. This is a potential source of VOCs in our food. They
also contaminate drinking water and leach into food from commercial food
packaging additives. A five-year
study
analyzed seventy different foods
for these chemicals. (79) They were found in at least one sample of all the
foods, ranging from ground beef, cola, bananas, and cheese. Does this mean that
we shouldn’t eat bananas? Not at all! Just try to avoid those in
styrofoam
or plastic packaging and rather buy organic
produce whenever you can.
VOCs
have been found to
interfere with cellular
membranes and cause diverse neurological effects. (80)
Studies
have also found a significant association between volatile organic
compound exposure and the increased risk of developing an autoimmune problem.
(81)
These
chemicals alter cell proliferation and tissue-specific function. The
pathological effects are more pronounced if exposure occurs over a longer
period of time. Chronic exposure results in deposits of the chemicals in organs
and then exaggerated immune system responses.
It is
extremely difficult to avoid VOCs in our food because almost every food product
that is available today is contained in, and protected by, some form of
packaging. The trick is to avoid packaging. Try to purchase fresh produce in
paper bags rather than plastic. Avoid any kind of
styrofoam
or plastic and make sure you never heat food in these. Use glass or ceramic
containers in the microwave. Avoid take-out food in plastic-lined boxes — or
better yet, avoid fast food altogether.
Organic
solvents
are liquids that dissolve a liquid, solid, or gas and are carbon-based. In
agriculture, solvents are commonly used in the isolation and preparation of
active ingredients for various agricultural products and pesticides, which
allow for slow, uniform drying of the product so that adequate penetration and
high spraying efficiency can occur. There are enormous
hazards
associated with solvents, and
they are almost all toxic if swallowed, inhaled, or are in contact with the
skin. (80)
Constant
exposure affects the central nervous system’s functioning, creating side
effects such as headaches, dizziness, blurred vision, and mood changes. Some common
organic solvents are acetone, ethyl acetate, heptane, methanol, ethanol, and
toluene.
N
ewer studies
have shown a link between organic solvents
and autoimmune conditions such as multiple sclerosis (MS) and autoimmune
hepatitis. (81)
The mechanism seems to be that organic solvents can alter cellular
proliferation, apoptosis, and tissue-specific functions. The amount and
duration of exposure directly influence the causation of disease. Long-term
exposure leads to solvent deposits forming in organs. This sets in motion an
immune reaction, inflammatory response, and tissue
injury
.
In
agriculture, solvents can contaminate soil, water, and food crops. People are
advised to thoroughly wash fresh produce in cold, running water before eating
it to avoid consuming solvent residue. Organic solvents such as hexane are also
used in the food industry to extract soluble components. For instance, they’re
used on coffee beans to decaffeinate the coffee and also to make soluble
instant coffee. We’d recommend purchasing whole coffee beans and grinding them
yourself for your daily coffee (5).
Persistent Organic Pollutants (
POPs
), Polyaromatic Hydrocarbons (
PAHs
), Organic
Solvents
, and PM25 air
pollution have been documented to have significant adverse neurological and
developmental/behavioral and respiratory effects (35abc, etc.)
.
Paint thinners or removers had a significant positive OR
for ALS (28,34).
PBDE (flame retardants)
exposure in childhood have been shown to have adverse effects on mental
development, psychomotor control, and IQ. (34)
Perfluorooctanoic
acid (PFOA) is a synthetic compound used in many food-related items. Because of
its unique properties of being chemically and thermally inert, having low
surface energy and high surface-active properties, it is used for many consumer
applications. A well-known one is as a component of non-stick cookware
manufactured with Teflon. It is also found in microwave popcorn packaging. It
can also be found in other everyday items such as food wrappers, pots and pans,
textiles, and grease.
Even
personal care products
like
waterproof mascaras and eyeliners
,
sunscreen, shampoo, and shaving cream
can
contain PFAS
They’re also used in firefighting foam on military
bases and in commercial airports. They’ve
contaminated drinking water sources
across the country
and
are also found in certain foods
.
It is a health
concern because it is highly toxic and can remain in the environment and the
body for a long time. Studies show that globally it can be found in almost the
entire population’s blood & 98% of Americans tested positive for it. Higher
blood levels are found in regions where water supplies are contaminated.
Perfluorinated
chemicals (PFOCs)
have been
linked
to
cancer and endocrine conditions in humans, such as thyroid disorders, low birth
weight, and chronic kidney disease. (82) The chemicals have also been linked to
autoimmune diseases
such as lupus,
colitis, multiple sclerosis, Crohn’s disease, diabetes type 1, and rheumatoid
arthritis. (83)
Women and children are especially vulnerable to the chemicals’ effects.
A critical effect in humans is an increase in blood cholesterol levels.
The
European Commission in 2018 asked for a scientific evaluation of the risks to
human health related to the presence of
perfluorooctane
sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) in food. The
investigation
found that the main
sources of chronic exposure to PFOA were seafood, dairy products, and drinking
water. (84)
You can avoid the first two by
following a delicious, healthy plant-based diet and the third one by investing
in a good water filter.
There are
several other ways to avoid these chemicals. Don’t use Teflon non-stick
cookware but rather use ceramic or cast-iron cookware. Avoid food wrappings
that have been coated with greaseproof coatings such as the takeout boxes at
fast-food stores.
Exposure to
EMF or wi-fi radiation
have been
shown to have significant developmental effects as well as causing cancer.
EMF exposure had a significant positive OR
for ALS,
Alz
., Parkinson’s(27d). Dental amalgam
(silver) fillings are documented to be the largest source of mercury in those
with such fillings, and EMF and/or Wi-fi have been documented to cause much
higher release of mercury vapor from such fillings- so
EMF
is a factor in all the many
chronic conditions caused by mercury exposure. Cell towers have also been found
to be significantly affecting
bird,
bee, and insect populations
that are drastically declining in the last
decade.
Certain
types of molds produce toxic mycotoxins that are harmful to humans and
livestock. Studies have shown a link between mycotoxins and autoimmune diseases
like rheumatoid arthritis, scleroderma, neuro-autoimmunity, systemic lupus
erythematosus (SLE), autoimmune diabetes, Sjogren’s syndrome, and psoriasis,
etc. (5b,40,42-45,52). Approx. 90 % of people who are suffering from chronic
tiredness have toxicity as the root cause and this includes toxicity from heavy
metals, pesticides, molds and mycotoxins. Besides being infected by dangerous
molds in their environment, a person can be exposed to mycotoxins when they
directly eat moldy food or consume products from animals that have been fed
contaminated feed. Aflatoxin and
Ochratoxin A
(Penicillium) are common in crops.
Contamination is caused by
poor storage of commodities and improper practices during the drying stage of
crop production. Aflatoxins are a family of toxins produced by certain fungi
that can be found in cereals such as corn, sorghum, wheat, and rice; oilseeds
like soybean, peanut, sunflower, and cotton seeds; spices, particularly chili
peppers, black pepper, coriander, turmeric, and ginger; and tree nuts such as
pistachio, almond, walnut, coconut, and Brazil nuts.
Aflatoxins target the
liver
and exposure to them has been
associated
with a higher risk of developing liver
cancer (47).
Aflatoxins
are extremely toxic and also cause serious neurological, immune, and
cardiovascular conditions (46,47, etc.).
Aflatoxins also have immunosuppressive
effects resulting in an increased susceptibility to infection and other chronic
conditions (46b).
Testing for
exposure to molds and mycotoxins in humans is simple- usually done with a urine
sample. Detox usually is done using binders like clay, charcoal, chlorella,
zeolite, cilantro, citrus pectin, and cholestyramine; or focusing on liver
detox support doing cleanses or using supplements like chlorella, milk thistle,
etc.
Cooking
does not destroy aflatoxins, so they need to be avoided and counteracted by
high dose Vitamin C (48).
Commonly found
intestinal parasites are flatworms, which include tapeworms and flukes,
roundworms, pinworms, and hookworms. (87,5b,52) Children often play in
environments that are contaminated, like sand and soil. A common way that
adults become infected with intestinal worms and parasites, however, is through
the consumption of undercooked meat sources like beef, pork, or fish.
Autoimmune diseases like celiac disease and IBD (inflammatory bowel disease),
etc. have been linked to parasites. Multiple studies show that infections from
bacteria, viruses, and parasites commonly trigger autoimmune diseases. Some of
the common parasites are Cryptosporidium, Giardia intestinalis, Cyclospora
cayetanensis
, and Toxoplasma gondii. Cryptosporidium is a
parasite that causes diarrheal disease in many people.
Plasmodium
is the broad name for the five
parasites that cause malaria. Plasmodium falciparum and Plasmodium vivax are
the two most deadly ones. Malaria is caused by parasites that are transmitted
to people through the bites of infected female Anopheles mosquitoes. These
parasites have been shown to cause many autoimmune responses such as severe
anemia and are a factor in
cancer(
87). A study from
Argentina followed 12 patients with multiple sclerosis (MS). They had all had
gastrointestinal infections caused by helminths (
roundworms,
tapeworms, flukes) (5b).
Testing is
mostly by stool sample. In addition to anti-parasitic medications such as
Ivermectin
(that has also been found effective at preventing and treating Coronavirus),
there are foods such as
garlic, pumpkin seeds, pomegranates, beets, and
carrots that have anti-parasitic activity plus herbs and essential oils that
have anti-parasitic effects.
Toxic
Chemicals commonly found in the Food Supply
Bisphenol
A (BPA) is a commonly used industrial. It is used mainly to manufacture
plastics and epoxy resins, and it is commonly found in household plastics such
as food containers and water bottles. Certain dental products and medical
devices may also contain BPA.
BPA can
easily leach into our drinking water and food — especially when the plastic is
exposed to heat. BPA is endocrine-disrupting (31) and
appears
to cause
several immune reactions that contribute to the development of
autoimmune disease (49).
BPA is thought to trigger
autoimmune degeneration of the sheaths that line nerves (49b), leading to
autism spectrum disorders, multiple sclerosis (MS), neuropathy, and
neurodegenerative disorders such as Parkinson’s disease. Some people and
children are much more susceptible than others to BPA.
Most
people get exposed to BPAs via their diet when it seeps into the food or beverage
from the container, especially after heating.
BPA is becoming widespread and is found throughout our environment, and
can be detected in the blood of nearly everyone tested. While it is not
possible to totally avoid BPA, you can decrease your exposure to it by
following these suggestions:
·
Use
glass, ceramic, or stainless- steel water bottles and food storage containers.
·
Never
microwave food or beverages in plastic containers.
·
Use
as few canned products as possible. Look for glass jars of beans, spaghetti
sauce, etc.
·
Buy
BPA-free baby bottles.
·
Don’t
cover food with plastic wrap or store it in plastic bags.
·
Ask
your dentist to use BPA-free composites on your teeth.
·
Follow
an anti-inflammatory diet.
·
Use
supplements that support immune health.
Aspartame
is a type of brain excitotoxin that is often added to food and beverages. It is
a popular, pervasive additive, particularly in the diet-food industry because
it acts as a zero-calorie sweetener.
It
is also used in many sugar-free medicines such as cough syrups and chewable
tablets. The body doesn’t process this type of artificial ingredient very well,
and it can trigger an immune reaction leading to inflammation and ultimately to
autoimmune issues.
In the
last ten years or so, many studies have shown aspartame’s adverse health
effects (50), but the FDA has continued to approve the substance, citing over a
hundred studies that say it is safe under certain conditions.
MDLinx
recently reported many of aspartame’s
negative effects on mood and headaches — particularly for those suffering from
migraines (50,51).
It has also been linked
to stroke and cardiovascular issues, as well as an increased risk of
dementia,
Parkinsons
,
Amyotrophic Lateral Sclerosis
,
epilepsy, etc. (50,51).
When
aspartame is broken down in the body, some of it produces methanol. In recent
years, aspartame has become the
largest
source
of methanol in the American diet (50,51b).
Small
amounts are harmless, but larger amounts are toxic because methanol degrades
into formaldehyde, which is a carcinogen and neurotoxin.
There is
a dangerous link between aspartame and autoimmune disease. Studies
have
found that daily consumption of
diet soda (containing aspartame) has been associated with a 36% higher risk of
developing metabolic syndrome and a 67% higher risk of developing type 2
diabetes (50,53).
In animal
studies
, aspartame has been shown to
lead to Hashimoto’s thyroiditis, an autoimmune disease where the immune system
systematically destroys the thyroid gland, causing it to eventually fail (54).
In one
case
of
a woman whose disease was brought on by excessive consumption of artificially
sweetened beverages.
Once the sugar substitutes were eliminated from her diet, the
thyroiditis resolved (54).
MSG
is another type of excitotoxin. Excitotoxins are a category of chemicals
(commonly amino acids) that overstimulate our neuron receptors and taste buds
(50). These receptors aid communication between brain cells. Excitotoxins cause
them to fire more quickly than usual. If this process goes on for too long,
such as if someone consumes large amounts of fast foods containing MSG, the
neurons can become exhausted and even die. The over-excited brain cells affect
mood, behavior, and can cause headaches. Many chicken products and Chinese
restaurant food contain MSG. A
study published
in
The Journal of Headaches
and Pain
showed that headaches occurred in 8 out of 14 people after
ingesting MSG, as opposed to just 2 out of 14 people after ingesting a placebo
(55).
Manufacturers
add MSG to food to intensify that savory umami flavor that’s so popular. Despite
pressure from various health organizations, MSG is still approved by the FDA in
the US. The Standard American Diet — appropriately referred to as SAD — is full
of processed foods loaded with additives, including the excitotoxin glutamate.
Watch for MSG in bottled sauces and salad dressings, processed chicken
products, crackers, crisps, and canned food.
There is
strong evidence that over-exciting our nerve receptors is harmful to the
neurons and certain parts of the brain (50). Researchers have long suspected
that some people’s fibromyalgia and ADHD symptoms are worsened by the use of
flavor enhancers and sweeteners containing excitotoxins (50, etc.). In 2001,
a study published
reported that the
fibromyalgia subjects were mostly free of symptoms after eliminating MSG and
aspartame from their diets (56).
When they
consumed MSG later, their symptoms reappeared. The action of these excitotoxins
may in extreme cases
trigger an autoimmune disease
such as
multiple sclerosis, ALS, and Parkinson’s (57,50).
Since
most processed foods contain excitotoxins, including baby food, eating a
whole-food plant-based diet is your answer to avoiding these harmful chemicals.
Fresh or frozen vegetables can be processed in a food processor for
infants.
Preliminary studies
have been done on
the importance of vitamin D for countering excitotoxin effects (58).
This vitamin appears to aid neurons in
lowering glutamate toxicity in cells. Make sure you get a little sunshine every
day or take a supplement.
Phenylalanine
naturally occurs in many protein-rich foods like milk, eggs, and meat. It is
also sold as a dietary supplement and is a component of
aspartame
. It is
an amino acid and, therefore, is one of the building blocks of proteins.
Because phenylalanine can be found in so many food products and medications,
the risks of excess consumption and toxicity are high, and some are more
susceptible than others (50). It can be especially dangerous for people with
the rare condition phenylketonuria (PKU). Individuals with PKU are unable to
process phenylalanine properly. Phenylalanine can cause intellectual
disabilities, brain damage, and seizures in people with PKU. There is a blood
test available for newborns to detect this if you want to check. Labels of
aspartame-containing foods and beverages must include a statement that informs
individuals with PKU that the product contains phenylalanine,”
notes
the
FDA. Any foods that contain aspartame also contain phenylalanine. For instance,
artificial sweeteners, including Equal and NutraSweet. It really is best to
avoid these altogether and focus on naturally sweetened foods like fruit.
Phthalates are the chemicals used to make
plastics flexible and soft. They’re also used as lubricants in cosmetics. They
can be found in food containers, beauty products, pharmaceuticals, toys, paint,
and shower curtains, for example. They can easily leach from the plastics and
contaminate our drinking water supply, food, and even the air we breathe
—especially if the plastic is heated. Diet is also a way of being exposed to
these chemicals.
Studies
have shown that diets
high in dairy and meat products exceeded the EPA reference dose for infants and
adolescents (61a).
The review of the literature demonstrated that DEHP in some meats, fats
and dairy products is consistently found in high concentrations and can
contribute to exceeding the exposure limits.
Phthalates are linked to asthma, breast cancer and obesity. There
is also a strong link to diabetes and heart disease. Furthermore, they can
cause reproductive damage and ADHD (61b).
A study conducted in Sweden pre-schools
found that children
absorb airborne phthalates emanating from plastic floor material by way of
their skin and respiratory tract.
(62)
The most
abundant plasticizers in preschool dust were the phthalates
DiNP
and DEHP. The levels of several substitute plasticizers were higher in newer
preschools.
A Chinese study
found that samples
collected from greenhouses and markets were all contaminated with PAEs.
(62b)
Phthalates are found in plastics and
cosmetics and have been proliferating rapidly in the use and in people.
Researchers have linked
phthalates
to
asthma,
attention-deficit hyperactivity disorder, breast cancer, obesity and type II
diabetes, low IQ, neurodevelopmental issues, behavioral issues, autism spectrum
disorders, altered reproductive development and male fertility issues.
(64).
At the
hormonal level, phthalates can modify the release of hypothalamic, pituitary,
and peripheral hormones. At the intracellular level, phthalates can interfere
with nuclear receptors, membrane receptors, intracellular signaling pathways,
and modulate gene expression associated with reproduction. Phthalates may
induce alterations in puberty, the development of testicular dysgenesis
syndrome, cancer, and fertility disorders in both males and females (65a).
Several phthalates have been classified as reproductive toxicants and
endocrine-disrupting chemicals based on their ability to interfere with normal
reproductive function and hormone signaling. Currently, the effects of
phthalates on male reproduction are better understood than the effects on
female reproduction, but recent work has established the ovary as a target of
phthalate toxicity. (65b)
Therefore,
exposure to phthalates represents a public health concern. (64,65)
Phthalates along with several other toxics have also been
shown
to
be a factor in the onset of lupus (63),
as they
are endocrine-disruptors,
and may also
cause abnormal sexual development and fertility issues. (31)
As a result, they’ve been linked to
infertility and pregnancy problems. They have also been linked to diabetes,
obesity, and cancer.
While it
is not possible to avoid phthalates altogether, you can certainly limit your
exposure to them. One way is to avoid fragranced products. Go for
“fragrance-free” or those that are perfumed with natural essential oils. Avoid
old plastic toys. Newer ones tend to comply with current regulations and are
largely phthalate-free. Also, NEVER heat your food in plastic containers. If
you’re microwaving it, transfer your food to a glass container to heat. Eat
organic produce as much as possible and filter your drinking water. (66)
Avoid
takeout food as much as possible. Aside from the obvious health issues such as
too much fat, fast foods contain large amounts of phthalates. This is partly
due to the packaging in which they are served. People who ate out regularly
were
shown
in
one study to have as much as 40% higher phthalate levels than people who ate
home-cooked meals. (67)
Grain-based takeout meals such as those consisting of mainly
bread, pasta, pizza, noodles, and rice were shown to contain the most
phthalates.
Dioxins
are pollutants commonly found in the environment. They are part of the
so-called “dirty dozen” — a cluster of dangerous chemicals identified as
persistent organic pollutants (
POPs
).
The highly toxic potential of dioxins, such as Agent Orange which affected huge
numbers of Vietnam War participants, makes them a particular concern (69).
Experiments have shown
that they affect a
number of bodily organs and systems. Short-term exposure to dioxins in humans
may cause skin lesions, like chloracne, irregular darkening of the skin, and
changed liver function (68).
Long- term exposure has been linked to
malfunctions of the
immune system including cancer
(69).
They not only have an immunosuppressive
action, but they also seem to
cause or make worse
autoimmune diseases,
infections, and other chronic conditions.
Dioxins can excite the immune system,
making it hypersensitive and leading to autoimmune diseases, allergies, etc.
(68,69).
Once
dioxins gain access into the body, they persist for a very long time (between
7-11 years) due to their chemical stability and absorbability into fatty tissue
where the body then stores them. Humans come into contact with dioxins mainly
through the food they eat that gets contaminated during the farming process.
The foods most packed with dioxins are meat, fish, shellfish, and dairy
products. Shall we say it again? Plant-based food is generally less
contaminated.
Animals
higher up in the food chain have a higher concentration of dioxins. In many
cases, dioxin contamination gets introduced through contaminated animal feed.
For example, incidences of increased levels of dioxin in milk traced their
roots back to citrus pulp pellets or fat utilized in the making of the animal
feed. A lot of dioxin exposure also occurs through atmospheric pollution via
medical waste incineration.
Due to
this high prevalence, many countries now actively monitor their food channels
for dioxin. This has very often reduced widespread contamination by early
detection.
These
chemicals cannot be totally avoided but like with the others, we can reduce our
level of exposure to them. Firstly, avoid using bleached coffee filters. More
than half of the dioxins contained in them get into your coffee. Avoid animal
products as far as you can and base your diet on grains, vegetables, and
fruits. Also avoid any bleached paper products like tea bags, paper towels, and
disposable baby diapers.
Glyphosate
is a broad-spectrum herbicide that is applied to food crops to kill weeds and
grasses. It has become one of the most widely used herbicides since its
introduction in 1974. It is not only used in farming, but also in forestry and
gardens. “Broad-spectrum” means that the chemical is non- selective and will
kill most plants. Roundup, made by the company Monsanto (now Bayer), is one of
the better-known glyphosate herbicides.
Exposure
occurs when the spray is inhaled or when it gets onto a person’s skin from
where it may be absorbed. In the time that this chemical has been in wide use,
the incidence of autoimmune diseases such as multiple sclerosis, type 1
diabetes, and inflammatory bowel disease has increased similar to glyphosate
use. Glyphosate causes autoimmune conditions and some
studies
suggest that there may be a link. (70)
Glyphosate
interrupts the functioning of the gut bacteria which is a common feature of all
autoimmune diseases, especially celiac disease. Celiac disease and gluten
intolerance are a growing problem worldwide and
research
suggests that glyphosate may be the main factor. (71)
It has been
shown to disrupt the gut bacteria in animals by killing beneficial bacteria and
allowing pathogens to proliferate. In fact, all celiac disease symptoms can be
explained by glyphosate’s known properties. This is because glyphosate may
interrupt the breakdown of protein in the gut — leaving large fragments that
the immune system will identify as foreign and attack — which, in turn, would
lead to the immune system launching its own attack.
Glyphosate
may also damage
the delicate walls of the
small intestine causing what is known as “leaky gut.” (71)
The
intestinal wall is covered with a protective mucus membrane that absorbs
nutrients and at the same time prevents harmful substances from accessing the
bloodstream. When the gut is leaky, it has openings in the lining of the gut
wall that allow bacteria and toxins to seep through. This causes an allergic
reaction and may trigger autoimmune reactions.
It has been established that leaky
gut
is a major step in the progression of most autoimmune
diseases
and it is present in most patients with autoimmune conditions.
Glyphosate,
being a strong antibiotic, also causes havoc on the gut bacteria, leaving the
gut and body susceptible to infections and autoimmune conditions.
A 2013 study
suggested that glyphosate may be
contributing to the rise in autism, Alzheimer’s, Parkinson’s, and more. (73)
Now that
you’ve read the bad news, here’s something positive for you: changing to an
organic diet as far as possible can rapidly lower the levels of glyphosate in
your body. A new
study
published in
Environmental Research showed reduced levels in just a week when subjects
switched to an organic diet (72)
Sugar
has been linked to an increase in inflammation levels in the body, increased
chronic disease and cancer, and increased mortality (74).
Refined sugars and refined carbohydrates such
as high-fructose corn syrup have little nutritional value and cause the blood
sugar levels to spike due to how quickly the body digests and absorbs them. A
healthy diet should, therefore, only contain natural sugars consumed as
wholefoods.
A study involving feeding
mice sugar water showed that increasing sugar intake increased their levels of
an inflammatory immune cell called Th17 (14). This worsened the autoimmune
diseases of the mice including Crohn’s disease and multiple sclerosis. Diabetes
is an autoimmune disease that is commonly associated with a high sugar intake.
Dairy
products and toxic metals exposures also are associated with
diabetes
. There is a clear link
between the consumption of dairy and gluten and autoimmune diseases, because
gluten and dairy are two notorious inflammatory agents (15).
If you are worried about the negative effects
that dairy may have and want to detox your body from dairy, you can do the
following: Use dairy milk alternatives such as almond milk and coconut milk ice
cream. Consider goat milk (or milk from cows with type A2 protein in milk)- has
different type protein from most cow’s milk-less inflammatory and problematic.
To ensure that you get enough calcium when you go dairy-free, incorporate
almonds, dark green leafy vegetables, sesame seeds into your diet. For protein,
intake eat high protein dairy free alternatives like quinoa, tofu, tempeh,
edamame and nuts. If you want to detox from gluten, you can take a probiotic
and eat probiotic-rich foods like sauerkraut, fermented vegetables, miso soup,
tempeh, pickles, coconut milk kefir, dairy-free yogurt, coconut water. Exercise
may also help with the detox process.
GMO stands for genetically modified organisms. This means that
scientists are altering the genetic makeup of crops by inserting a gene or two
into individual cells in a lab. There are several reasons why GMOs are linked
to the development of autoimmune diseases. They contain more pesticides than
non-GMOs because GMOs are modified to use more herbicides without killing the
crops. As we know, pesticides can cause toxicity leading to an autoimmune
response. Also, many GMOs have been designed to produce their own insecticide.
This has negative consequences for those who eat these foods. Evidence shows
that it
is damaging the
intestines and causing leaky gut, making individuals more susceptible to
autoimmune disorders (16,20). This is because an unhealthy digestive tract
suppresses the immune system.
An estimated 92% of corn and 94% of soy grown in the U.S. are
genetically modified
1
,
Studies
funded by consumer-oriented organizations, such as The Institute for
Responsible Technology
3
and The Environmental Working Group,
4
have found an alarming number of
connections between GMOs and health problems, including intestinal damage,
inflammation, higher rates of disease, and even death(16).
Glyphosate
use has increased 16-fold
5
since
the Roundup® ready seeds were introduced in the 1990s. This statistic should
worry all of us because the World Health Organization released a report
6
stating
that glyphosate probably causes cancer in humans. In fact, earlier this year a
California jury awarded one couple millions of dollars in damages on the
grounds that exposure to Roundup® caused9 their cancers. It was the third case
in that state alone.
7
(16)
Another problem caused by the widespread use of glyphosate in
our crops is that it has led to a sharp increase in glyphosate-resistant weeds.
These “superweeds” require even greater herbicide use and are often combated
using older, more dangerous herbicides, such as 2, 4-D, a chemical that has
been linked
8
with
non-Hodgkin’s lymphoma, Parkinson’s disease, endocrine disruption, and
reproductive problems.(16)
Many GM crops, including corn, were engineered
to produce their own insecticide, called
Bt
-toxin, by
combining the plant’s DNA with DNA from bacteria.
Bt
-toxin
kills insects by destroying the lining of their digestive tracts. The poison is
not specific to insects and also pokes holes in human cells
9
, damaging the intestines and causing leaky gut,
which is a precondition for developing an autoimmune disease. The growing body
of evidence
10
that GMOs are dangerous prompted the
American Academy of Environmental Medicine (AAEM) to publicly warn that “it is
biologically plausible for Genetically Modified Foods to cause adverse health
effects in humans.”
GM plants are also engineered to enhance plants’ natural “plant
protectors,” including prolamins, agglutinins, digestive enzyme inhibitors, and
saponins. These chemicals contribute to leaky gut, gut dysbiosis, and
inflammation, all of which
negatively impact
those of us
with an autoimmune disease or inflammatory condition.
Glyphosate, the herbicide used on GM crops, is
also a potent chemical that can attack the bacteria in your gut. Unfortunately,
the good bacteria in your gut, the kind that help with digestion and keeping
the bad bacteria in check, are more likely to be susceptible to glyphosate,
while the bad bacteria, including strains that cause salmonella and botulism,
are highly resistant to glyphosate
11
. This means that eating GMO foods can decrease
your healthy bacteria and increase the bad bacteria, putting you at risk for
Candida overgrowth
, leaky gut, and
inflammation, which can contribute to autoimmune disease.
(16)
Options: choose organic or local non-GMO vegetables; eat only
grass- fed meat and eggs, use EWG health guide, support your liver (NAC, ALA,
vit C, E, zinc, selenium, CoQ10, milk thistle extract) & More Information
(18).
The
most important factors in preventing any chronic autoimmune condition or
reversing autoimmune conditions are:
good diet including anti-inflammatory foods; avoiding vitamin &
mineral deficiencies, avoiding toxic exposures- testing where needed and
detoxing toxic exposures; checking and balancing hormones, high dose vitamin C
for chronic conditions, and regular exercise.
References:
(1)
Does Vitamin C Influence Neurodegenerative Diseases and
Psychiatric Disorders?
Nutrients
2017 Jul; 9(7): 659.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537779/
&
High
Dose Vit C for Chronic Conditions
&
www.myflcv.com/VitCdoc.html
;
(2) B. Windham, DAMS Intl,
Mercury Connection to Chronic Health Conditions
;
(3)
B. Windham, DAMS Intl,
Toxic Metals Connection
to Chronic Health Problems
&
Health Effects of Toxic Metals
;
&(c)
Advances
in metal-induced oxidative stress and human disease
. Toxicology. 2011 May
10;283(2-3):65-87.
Jomova
K,
Valko
M.;
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Toxic Metals
Connection to Neurological Conditions
(5
) (a)
Top 26 Foods on the Supermarket Shelves to Prevent
and Reverse Chronic Inflammation and Autoimmune Disease
, Jonathan, Otto, 2019; & (b)
The root causes of
autoimmune disease and how to remove them from your body
By: Jonathan Otto ,
https://podbay.fm/p/health-secrets-podcast
&
(c)
23 Toxic Threats in Our
Food that Trigger Autoimmune Disease & How to Reverse their Effects
By: Jonathan Otto
(these have lots of credible documentation
from NIH
Pubmed
)
https://issuu.com/jonathanottofanpage/docs/find_the_root_cause___treatment_of_autoimmune_dise
https://issuu.com/jonathanottofanpage/docs/autoimmune_diseases_and_nutrition_e
-----------------------------------------------------------------------
(6)
Treating
Autoimmune Conditions Naturally-
according to
a
recent study
by
researchers
at
NYU Langone Health In New York
City
.
https://www.newsmax.com/health/health-news/lupus-natural-treatment/2021/01/25/id/1007068/?ns_mail_uid=cc9848a3-3fc2-4960-b6f7-41f28f6ba994&ns_mail_job=DM185330_01272021&s=acs&dkt_nbr=010502wly267
(7)
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,
2016 Dec;
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Ravindran
Jayaraj
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https://foodqualityandsafety.wfp.org/fumigation/
(11)
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Here:
Home Page
>
Pests and Pesticides
>
Reducing Pesticide Exposure
(13)
B Windham, DAMS Intl,
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, 2019.
(14)
High sugar intake worsens autoimmune
disease in mice,
NIH Research Matters
,
August
27, 2019,
https://www.nih.gov/news-events/nih-research-matters/high-sugar-intake-worsens-autoimmune-disease-mice
When faced with
a crippling autoimmune disease, this teen totally rehabbed her diet.
https://www.goodhousekeeping.com/health/diet-nutrition/a40053/diet-reversed-autoimmune-condition/
(19) B Windham, DAMS Intl, (Ed),
Health Effects of Pesticides
,
2020.
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;
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& (b)Potpourri of
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The Nevada Center for Alternative
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; &(c)
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&
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; AromaticsInternational Wellness
Blends:
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; &
HealthPrep
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